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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure

Fig. 6

miR-126-3p-hucMSCs-exosomes treatment affected ovarian structure in rats with chemotherapy-induced POF. A. Representative photograph of rat reproductive organs in Normal group, POF group, hucMSCs-exosomes group, NC-hucMSCs-exosomes group, and miRNA-126-3p-hucMSCs-exosomes group. HE staining was performed to observe the histology changes and the number of follicles at different stages of rat ovaries at 4 weeks after miR-126-3p-hucMSCs-exosomes treatment (B × 40, C × 100, D × 200). n = 10 for each group

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