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Table 1 Summary of OCT4 associated lncRNAs

From: The roles of long noncoding RNAs in the regulation of OCT4 expression

LncRNA

Location (Human)

Mechanism

Cell line

Nude mice xenograft tumour model

Human sample

Refs.

mmu-OCT4-pg4

Mice

RNA-binding protein FUS; Histone methyltransferase SUV39H1

mice ESC cell(Isolated from C57BL/6 mouse embryos)

[13, 14]

hsa-OCT4-pg3

12p13.31

Same as above

OVACR-3

[14]

mmu-OCT4-pg5

Mice

Histone methyltransferase Ezh2

Breast cancer cell line:

MCF-7

[15]

CCAT2

8q24.21

OCT4-pg1; miR-205

Breast cancer cell line:

MCF-7, MDA-MB-231, etc.

MDA-MB-231

Breast cancer

[16]

Oplr16

Mice

Intrachromosomal loop; DNA demethylase TETs

iPSC (reprogramed from mice fibroblast by OSKM)

[20]

Osblr8

Mice

Same as above

iPSC (same as above), mice ESC cell line E14

[21]

Peblr20

Mice

Same as above

iPSC(same as above)

[22]

DANCR

4q12

miR-216a-5p;

miR-335;

miR-145

Breast cancer cell line:

MCF-7, MDA-MB-231, etc.; urothelium cell line SV-HUC-1

MDA-MB-231

Breast cancer

[5,6,7, 23]

SLCO4A1-AS1

20q13.33

miR-335-5p

Bladder cancer cell lines: EJ, T24 andRT4;

T24

Bladder cancer

[8]

Linc00337

1p36.31

miR-145

Cervical cancer cell lines: HeLa, SiHa, CaSki, etc.; sphere-forming subpopulation isolated from HeLa cells

sphere-forming subpopulation

Cervical cancer

[9]

LincRNA-ROR

18q21.31

miR-145

CD44+/CD133+ subpopulation isolated from Prostate cancer cell lines Du145 and 22RV1

CD44+/CD133+ subpopulation

Prostate cancer

[24, 25]

SNHG3

1p35.3

miR-3619-5p

Gastric cancer cell lines SGC7901 and BGC823; mice ESC cell line AB2.2

Gastric cancer

[27, 28]

SNHG7

9q34.3

miR-34a

Breast cancer cell line:

MCF-7, MDA-MB-231, etc.

Breast cancer

[29, 30]

SNHG20

17q25.2

miR-197, Lin28

Oral squamous cell carcinoma cell lines SCC9, SCC15, SCC25, etc.

SCC15

Oral squamous cell carcinoma

[31]

LX8-SINE B2

Mice

Regulated by OCT4

mice ESC cell line E14

[32]

NEAT1

11q13.1

Regulated by OCT4; miR-204-5p

Lung cancer cell lines A549 and CL1-0; Bladder cancer cell line T24

Ovariectomized obese mouse model induced by high fat diet

Lung cancer

[10, 33]

ES1

6p23

mutually regulated with OCT4

人Breast cancer cell line: MDA-MB-231, SKBR3, etc.

Breast cancer

[34, 35]

MIAT

22q12.1

Same as above

mice ESC cell line E14;

Leukaemia/Lymphoma cell lines BALL, DLBL, etc.

Breast cancer cell line:

MCF-7, MDA-MB-231, etc.

Leukaemia; Breast cancer

[37,38,39]

MALAT1

11q13.1

Same as above

Lung cancer cell lines A549 and CL1-0; Colorectal cancer cell lines COLO205, HCT‐116, etc.

HCT‐116

Lung cancer

[10, 41]

PSORS1C3

6p21.33

Share promotor with OCT4

Teratoma cell line NT2; A549; Kidney cancer cell lines CRL-1932/1611

Clear cell carcinoma of kidney

[44,45,46]