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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Bone marrow mesenchymal stem cells inhibit hepatic fibrosis via the AABR07028795.2/rno-miR-667-5p axis

Fig. 5

Rno-miR-667-5p inhibits fibrosis in HSC-T6 cells. A lnc-BIHAA1-miRNA interaction network. B qRT-PCR showing the five dysregulated miRNAs targeting lnc-BIHAA1 in the lnc-BIHAA1 overexpressing HSC-T6 cells. C qRT-PCR showing the expression of miRNAs with the most upregulated and downregulated fold change in hepatic fibrosis rats. D qRT-PCR showing the overexpression of rno-miR-667-5p mimics in HSC-T6 cells. E CCK-8 assay showing the effect of rno-miR-667-5p overexpression on the activity of TGF-β1 induces HSC-T6 cells. Expression of fibrosis-associated genes detected by qRT-PCR (F), WB (G), and IHC (L). Magnification, 200×. H qRT-PCR showing the inhibitory deficiency of rno-miR-667-5p inhibitors. I CCK-8 assay showing the effect of rno-miR-667-5p suppression on the activity of HSC-T6 cells. Expression of fibrosis-associated genes detected by qRT-PCR (J), WB (K), and IHC (M). Magnification, 200×

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