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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exosome from indoleamine 2,3-dioxygenase-overexpressing bone marrow mesenchymal stem cells accelerates repair process of ischemia/reperfusion-induced acute kidney injury by regulating macrophages polarization

Fig. 6

Effect of MSCs-Exo-IDO on macrophage polarization. HLA-DR-positive A and CD206-positive B cell population in LPS-induced RAW264.7 cells treated with or without MSCs-Exo were detected by flow cytometry (n = 3/group). Quantization diagram as shown in the right. C ELISA was used to detect the secretion of inflammatory factors IL-1β, IL-6, TNF-α and IL-10 in LPS-exposed RAW264.7 cells with or without MSCs-Exo. Mean ± SD was used for histogram presentation (n = 3/group). **P < 0.01

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