Fig. 2

Characteristics of immune microenvironment in diabetic wound. a Heat map of immune pathway in db wound compared with that in non-db wound at 8 h, 10 days and 14 days. b Heat map of important immune factors in non-db/db wound at 0 h, 8 h, 2 days, 6 days, 10 days, and 14 days. c Proportion of main immune cells in non-db/db wound at 0 h, 8 h, 2 days, 6 days, 10 days, and 14 days. The data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001. N Non-diabetic mice group, D Diabetic mice group