Fig. 5From: Overexpressing HPGDS in adipose-derived mesenchymal stem cells reduces inflammatory state and improves wound healing in type 2 diabetic micehADSCHpgds regulates inflammatory environment. a Immunohistochemical stainings for Ly-6 g and CD8 in the tissue surrounding the wound at 3 days. Average number of positive cells per group was quantified. Red arrows indicate positive staining cells. b Immunofluorescence of F4/80, CD206 (Blue, DAPI; red, F4/80; green, CD206) in the healing skin within one millimeter to the healing edge at 7 days. Average area of positive fluorescence per group was quantified. c IL-1β (i), IL-6 (ii), TNF-α (iii) and iNOS (iiii) mRNA expressions were quantified at 7 days. The data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001. n = 5. CTL Control, means treatment with PBS; a, b scale bar = 100 μmBack to article page