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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Overexpressing HPGDS in adipose-derived mesenchymal stem cells reduces inflammatory state and improves wound healing in type 2 diabetic mice

Fig. 6

hADSCHpgds conditional medium or PGD2 promotes M2 polarization. ai Expression of CD206 in LPS-induced macrophage after treated with hADSCHpgds CM for 24 h was detected by qRT-PCR. VEGF (aii) and IL-1β (bi), IL-6 (bii) and TNF-α (biii) mRNA expressions in LPS-induced macrophage were quantified by qRT-PCR. mRNA expressions of CD206 (ci), VEGF (cii), IL-1β (di), IL-6 (dii) and TNF-α (diii) in LPS-induced macrophage after treated with PGD2 (50 μM) for two days was detected by qRT-PCR. The data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001. n = 4. PBS Phosphate buffer saline

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