Infarct-preconditioning exosomes of umbilical cord mesenchymal stem cells promoted vascular remodeling and neurological recovery after stroke in rats

Table 1 Group allocation and animal numbers

Technique for study	Sham	MCAO	EXO	N-EXO	I-EXO
EXO injection	–	–	n = 35	n = 35	n = 35
Died	–	n = 2	n = 2	n = 1	n = 2
Excluded	–	n = 1	n = 1	n = 2	n = 2
TTC	n = 3	n = 3	n = 3	n = 3	n = 3
MRI	n = 3	n = 3	n = 3	n = 3	n = 3
Tunel	n = 3	n = 3	n = 3	n = 3	n = 3
mNSS	n = 9	n = 9	n = 9	n = 9	n = 9
MWM	n = 10	n = 10	n = 10	n = 10	n = 10
IF	n = 3	n = 3	n = 3	n = 3	n = 3

MCAO middle cerebral artery occlusion, EXO normal exosome, N-EXO exosomes from UCMSCs which are preconditioned by normal cerebral tissue extracts, I-EXO exosomes from UCMSCs which are preconditioned by cerebral infarcted tissue extracts, TTC 2,3,5-triphenyl tetrazolium chloride, MRI cranial magnetic resonance imaging, mNSS modified Neurological Severity Scores, MWM Morris water maze, IF immunofluorescence

ISSN: 1757-6512