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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy

Fig. 2

The comparison of cellular properties between normal and diabetic BMSCs. The CCK-8 assay (a) showed that the cellular viability of DM-derived BMSCs was significantly worse than that of non-DM rats (n = 6). The levels of VEGF (b) and IGF-1 (c) in the medium were measured to reflect the paracrine function of BMSCs (n = 5). According to the DHE staining (d, e) and JC-1 staining (f, g), diabetic BMSCs had higher ROS level and mitochondrial dysfunction than nondiabetic BMSCs (n = 5–6). *P < 0.05 versus nondiabetic BMSCs group.

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