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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Mesenchymal stem cell-derived extracellular vesicles protect retina in a mouse model of retinitis pigmentosa by anti-inflammation through miR-146a-Nr4a3 axis

Fig. 7

MSC-EVs suppress inflammation in vitro. A TUNEL staining of 661W cells co-cultured with inactive-BV2, LPS-activated-BV2 or LPS-activated BV2 + EVs. 661W cells were stained with DAPI (blue, bottom panel) and apoptotic cells were labeled with TUNEL staining (green, top panel). B The percentage of TUNEL positive 661W cells over DAPI positive cells in the three groups. C-H mRNA expression of Arg1 (C), Nr4a3 (D), IL-1β, TNF-α, IL-6 (E), Chil3 and Retnla (F) in the treated group relative to that of the untreated group. Data are represented as mean ± S.E.M. One-way ANOVA and Student’s t-test was applied for statistics

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Stem Cell Research & Therapy

ISSN: 1757-6512