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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Infusion of two-dose mesenchymal stem cells is more effective than a single dose in a dilated cardiomyopathy rat model by upregulating indoleamine 2,3-dioxygenase expression

Fig. 1

Two-dose intravenous administration of hUCMSCs improves cardiac function in DCM rats. A A diagram illustrated the experimental design. B Kaplan–Meier survival curves of four groups of rats. C Representative images of M-mode echocardiography. D, E, G, H Echocardiography analysis of diastolic function (IVRT, E/E′), systolic function (EF%), and left ventricular internal diameter at end diastole (LVIDd). F Representative images of hematoxylin and eosin (H&E) staining in rat hearts. H&E, the upper images scale bar = 3 cm, the bottom images, scale bar = 100 μm. Data are represented as mean ± SEM of each group (N = 3–10 rats per group) from at least two separate experiments. *P < 0.05, **P < 0.001, ***P < 0.001 by one-way ANOVA

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Stem Cell Research & Therapy

ISSN: 1757-6512