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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Infusion of two-dose mesenchymal stem cells is more effective than a single dose in a dilated cardiomyopathy rat model by upregulating indoleamine 2,3-dioxygenase expression

Fig. 4

Treatment with IDO-OE hUCMSCs alters the frequency of different subsets of CD4 + T cells in the spleen and mediastinal LNs of DCM rats. A, B Representative flow cytometry dot plots and quantitative analysis of Tregs in the spleens. C–E Quantitative analysis of Th1, Th2, and Th17 proportions in the spleens. F, G Representative flow cytometry dot plots and quantitative analysis of Tregs in the lymph nodes. H–J Quantitative analysis of Th1, Th2, and Th17 proportions in the lymph nodes. Data are mean ± SEM of each group (N = 3–5 rats per group) from at least three separate experiments. *P < 0.05, **P < 0.001, ***P < 0.001 by one-way ANOVA

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Stem Cell Research & Therapy

ISSN: 1757-6512