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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic rats

Fig. 4

Multiple pre-ADSCs infusions ameliorated long-term T2D induced diseases of kidney. Serum creatinine, blood urea nitrogen, and urine ACR of each group were detected (A–C). Representative kidney sections by H&E, PAS, and Masson’s trichrome staining; bars = 10, 20 and 20 μm (D). Histopathological damage scores and tubular damage score were graded using H&E-stained sections (E, F). Glomerulosclerotic injury was graded using PAS-stained sections (G). Interstitial fibrosis was graded using Masson-stained sections (H). Immunohistochemical staining and quantification of α-SMA and col1 areas, bars = 50 and 20 μm (I–K)

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Stem Cell Research & Therapy

ISSN: 1757-6512