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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic rats

Fig. 5

Multiple pre-ADSCs infusions ameliorated long-term T2D induced diseases of liver. Representative liver sections by H&E, PAS, and Masson’s trichrome staining; bars = 50, 50 and 20 μm (A). Levels of serum ALP, ALT, AST, LDL-C and TG of each group were evaluated (B). Histopathological damage scores were graded using H&E-stained sections (C). Ratio of Sirius Red-positive area to total area (D). Quantitative reverse transcriptase polymerase chain reaction analysis of gene expression in liver tissue from control, T2D, ADSCs and pre-ADSCs groups (E, F); results are presented relative to those of control rats, set as 1. N = 6 rats per group; *P < 0.05, **P < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512