Fig. 7From: Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic ratsMultiple pre-ADSC infusions changed the phenotypes of macrophages in the target organs in long-term T2D complication rats. Representative Arg1-positive cells in pancreas, adipose, lung, renal, and liver tissue by immunohistochemistry; bars = 20 μm (A). Quantitative reverse transcriptase polymerase chain reaction analysis of gene expression in the kidney (B), liver (C), and lung (D) tissue from control, T2D, ADSCs and pre-ADSCs groups; *P < 0.05, **P < 0.01Back to article page