Fig. 4From: iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretionIR-iPSCs manifest increased cellular oxidative stress. A Gene ontology for upregulated genes in IR-iPSCs individually compared to IS-iPSCs obtained by RNA-Seq. B ROS quantification using the DCFH-DA by flow-cytometry in basal states showed increased expression in IR-iPSCs. C Annexin V quantification by flow-cytometry in iPSCs-treated with 0.5Â mM H2O2 showed increased susceptibility of IR-iPSCs to oxidative stressBack to article page