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Fig. 10 | Stem Cell Research & Therapy

Fig. 10

From: ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism and inhibiting the NF-κB pathway by the secretome

Fig. 10

Schematic depiction of the underlying mechanisms by which VEGF-C-stimulated ADSCs alleviate chronic colitis via lymphangiogenesis and immunomodulatory effects. VEGF-C-stimulated ADSCs could simultaneously improve lymphatic drainage (“OUT”) and inhibit the inflammatory response (“IN”) by activating VEGF-C/VEGFR-3-dependent signals and suppressing the NF-κB pathway

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Stem Cell Research & Therapy

ISSN: 1757-6512