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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Multi-omics analysis of an in vitro photoaging model and protective effect of umbilical cord mesenchymal stem cell-conditioned medium

Fig. 2

Functional annotation of differential proteins and their association with the transcriptome after UVB irradiation. a Significant distribution of differential proteins. The X-axis represents the fold difference in protein expression (take log2), the Y-axis represents the corresponding − log10 (Q-value), the red dots indicate proteins with increased expression and the green dots indicate proteins with decreased expression. The grey point indicates no significant change, where fold change > 1.2 Q-value < 0.05. b Differential protein KEGG pathway enrichment analysis. The X-axis represents − log10 (corrected p value): the larger the value, the greater its significance. The ordinate displays the KEGG pathway name. c, d, e Differential protein GO pathway enrichment analysis. f Joint analysis of differential proteins and transcriptomes. The Y-axis represents each pathway, the number of proteins associated with the entry is shown in parentheses, the X-axis indicates the enrichment factor; the bubbles of different shapes represent the data of different omics, and the circles represent the enrichment results of the proteome. Diamonds represent the enrichment results of the transcriptome. The size of the bubble represents the number of differential proteins or genes enriched in the term; the colour represents the significantly enriched p value. The larger the enrichment factor, the greater the proportion of differential proteins or differential genes in this type of function; the smaller the p value, the more significant the enrichment in this type of function

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