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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models

Fig. 2

α-Syn regulates MSC stemness and differentiation potential. A Expression levels (determined by quantitative RT-PCR) of the stemness markers OCT4, NANOG, SOX2, and NOTCH increase after 24 h incubation with 0.1 μM and 0.5 μM α-syn, but decrease on treatment with higher α-syn concentration. B–D Quantitative RT-PCR shows that α-syn treatment does not affect the expression levels of differentiation markers for B osteogenesis (SMURF1, SMURF2), C adipogenesis (PPARG, RHOA), and D chondrogenesis (HAT1, BMP4)

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Stem Cell Research & Therapy

ISSN: 1757-6512