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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models

Fig. 4

miR-374b and miR 376-3p regulate stemness of α-syn-associated MSC priming for targeting KLF15. AC Quantitative RT-PCR for KLF15-related miRNA shows a decrease in miR-374b and miR-376-3p expression levels but no significant change in that of miR-885-3p in α-syn-treated MSCs compared to those in control MSCs. D Quantitative RT-PCR analysis shows that downregulation of KLF15-related miRNA leads to increased mRNA levels of KLF15. Data are presented as mean ± SE. *P < 0.05; **P < 0.01

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