Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Systemic proteomics and miRNA profile analysis of exosomes derived from human pluripotent stem cells

Fig. 2

The top-loaded proteins in exosomes were involved in sophisticated network regulation. A Screening of the top-expressed candidate proteins from TMT and label-free protein pools under the conditions of high FDR confidence, mascot score > 60, and abundance > 100 (red dots) and abundance in each sample > 0 (green dots). Yellow dots represent the top-loaded proteins of exosomes. B Expression abundance curve of the three exosome types and the top ten loaded proteins in exosomes. C–E KEGG analysis of the top-expressed proteins in hESC-Exos, hiPSC-Exos, and hUC-MSC-Exos, respectively, ranked from high to low -Log10(P-value). The red bar represents the -Log10 (P-value) and the blue dot the proportion of candidate genes in the total pathway-related gene pool. F–H PPI analysis of top-expressed proteins in hESC-Exos, hiPSC-Exos, and hUC-MSC-Exos, respectively, according to the KOBAS algorithm. The color of the histogram corresponds to the color of the gene clusters in the PPI network

Back to article page