Fig. 3
From: Cancer cells as a new source of induced pluripotent stem cells
Applications of cancer-iPSCs.Cancer-iPSCs can help study cancer biology by investigating cancer-related genes and cell-to-cell interactions in the tumor microenvironment and are being used as a CSCs model due to the low deficient number of these cells in tumor bulk. They have biomedical applications such as finding new early biomarkers, screening drugs, and introducing new therapeutic agents. These cells can be a candidate in regenerative medicine in suicide gene therapy or some therapy applications after gene editing. However, they are very far from being used in clinics