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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis

Fig. 7

HUCMSCs attenuated ROS production and mitochondrial aberrations in vitro. A The diagram of the coculture system of HUCMSCs and CCSMCs. Representative immunofluorescence (× 200) (B) and quantification (C) of ROS in CCSMCs of each group. (D) The morphology of the mitochondria in CCSMCs analyzed by TEM. Original magnification × 5.0 k and × 10.0 k. Data are expressed as means ± standard deviation. *P < 0.05 versus the control group; #P < 0.05 versus the HG group. HUCMSCs human umbilical cord mesenchymal stem cells, CCSMCs corpus cavernosum smooth muscle cells, Con control, HG high glucose, Fer-1 ferrostatin-1, ROS reactive oxygen species, IOD integrated option density, TEM transmission electron microscope

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