Fig. 1
From: Connective tissue growth factor promotes cementogenesis and cementum repair via Cx43/β-catenin axis
CTGF promoted the repair of root resorption in vivo. A Representative images of HE showed the morphology of distal buccal roots of maxillary first molars. B Quantification of the area of the resorption lacunae labelled in A by yellow dotted line in CTGF-treated rats relative to the untreated rats. Statistical significance is indicated. *p < 0.05. C Construction the 3D model of the buccal distal root in the left maxillary first molar by mimics 21. The fuchsia area was reconstructed by the method mentioned in Additional file 2: Fig. S2E. The fuchsia area indicated the root resorption area. The resorption lacunae of the compressive root in the CTGF-stimulated rats were smaller than those of the untreated rats. Black arrows pointed to resorption craters. D Quantification indicated the smaller resorption lacunae in CTGF-treated rats relative to the untreated rats. Statistical significance is indicated. *p < 0.05