Fig. 7
From: Connective tissue growth factor promotes cementogenesis and cementum repair via Cx43/β-catenin axis
CTGF triggered β-catenin signalling in dose-dependent manners. A Western blotting demonstrated the abundance of β-catenin and active β-catenin in hPDLSCs treated with the concentration-ascending CTGF (0, 10, 20, 50 ng/ml). B, C Bar chart showed the protein abundance of β-catenin and active β-catenin in A ratio to the untreated control. Data are obtained from three independent images. n = 3, *p < 0.05. D Representative IF images of β-catenin staining, in hPDLSCs that were untreated, treated with CTGF. E Representative IHC staining illustrated that the abundance of active β-catenin in CTGF-treated hPDLSCs. active β-catenin, red; nucleus, blue; green, cytoskeleton. F A bar chart represented the means of IOD of active β-catenin. *p < 0.05. G Representative IF staining illustrated that the abundance of active β-catenin in CTGF-treated periodontal tissues. active β-catenin, red; nucleus, blue