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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Hsa_circ_0001485 promoted osteogenic differentiation by targeting BMPR2 to activate the TGFβ-BMP pathway

Fig. 1

Expressions of hsa_circ_0001485 in BMSC osteogenic differentiation. A KEGG analysis of differentially expressed circRNA host genes in the BMSC-14d group. B GO enrichment analysis of differentially expressed circRNA host genes in the BMSC-14d group. C Analysis of TGFβ and BMP pathways using GSEA. D qPCR was used to verify the circRNA expression of BMSCs at 0, 3, 7, and 14 d of induction. E The structure of hsa_circ_0001485. F The agarose gel electrophoresis detects the form of hsa_circ_0001485. G Sanger sequencing results of hsa_circ_0001485, in which the arrow indicates the cyclization site. H qPCR detect has the expression of hsa_circ_0001485 in BMSCs and MG63 and hFOB 1.19 cells. The results are representative data from three replicates, and the data mean ± SD (ns, no statistical significance; *P < 0.05; **P < 0.01; ***P < 0.001)

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