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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

Fig. 8

Assessment of potential influences of baseline patient characteristic, baseline wound size and wound surface area reduction during the screening period on response to treatment. Baseline patient characteristics and baseline wound surface area in all treated patients, responders and non-responders. A–B Comparisons of baseline patient characteristics (A) and of wound surface area reduction during screening and of wound surface area at baseline (B) between all treated patients, responders and non-responders. Depicted are Tukey’s boxplots (except for gender ratio); n = 23 (all patients; ankle-brachial index: n = 22), n = 17 (responders; ankle-brachial index: n = 16), n = 6 (non-responders). Kruskal–Wallis tests followed by Dunn’s multiple comparisons revealed no statistically significant differences between groups (p > 0.999 for all comparisons except for ankle-brachial index responders vs. non-responders: p = 0.697). C Spearman’s rank correlation analysis between wound surface area reduction during screening and wound surface area reduction from baseline at week 12. *Asterisk denotes a patient whose screening period lasted 118 days, as compared to 42–68 days (median 49 days) for the other patients

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