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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice

Fig. 7

Relative protein expression of VEGFA, HIF1α, GDF9, p-Akt, and Akt genes in non-grafted and grafts. Data were represented as mean ± SEM and analysed by one-way ANOVA and Fisher’s LSD post hoc test. P value references: *P < 0.05. Statistical significance is also expressed using different letters, a vs. b P < 0.05. VEGFA, vascular endothelial growth factor A; HIF1α, hypoxia-inducible factor-1α; GDF9, growth differentiation factor 9; p-Akt, phosphor-protein kinase B; Akt, protein kinase B; OT, ovarian tissue transplantation; N-MSCs + OT, normoxic-treated HucMSCs and ovarian tissue co-transplantation; H-MSCs + OT, hypoxia-treated HucMSCs and ovarian tissue co-transplantation

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