Fig. 6
From: TNFAIP6 defines the MSC subpopulation with enhanced immune suppression activities
TNFAIP6+ MSCs have enhanced anti-inflammatory activities in the mouse model of acute inflammation. A Serum level of IL-6, TNF-α, IFN-γ, and IL-1β was determined after 24 h post-LPS stimulation via ELISA (n = 8). B The total cell number in BAL was determined after 24 h post-LPS stimulation by flow cytometry (n = 8). C The neutrophil number in BAL was determined as CD45+CD11b+Ly-6G+Ly-6Cmed after 24 h post-LPS stimulation by flow cytometry (n = 8). D The MPO activity was quantified after 24 h post-LPS stimulation (n = 8). E The CD45+ cells in the lung were measured after 7 days post-LPS stimulation flow cytometry (n = 8). F Representative figures for HE staining of lung tissues after 7 days post-LPS stimulation. * indicates P < 0.05. TNFAIP6 tumor necrosis factor alpha-induced protein 6; IL-6 interleukin 6; TNF-α tumor necrosis factor alpha; IFN-γ interferon gamma; IL-1β interleukin 1 beta; BAL bronchoalveolar lavage; and MPO myeloperoxidase