Fig. 2

H-CM and P-CM enhanced the angiogenic activities of ECs. a The proliferation of ECs exposed to H-CM and P-CM was tested by CCK-8 assay (n = 3). b The migration of ECs stimulated by H-CM and P-CM was detected by transwell assay (scale bar, 100 μm). c Quantitative analysis of the migrated cells in b (n = 5). d Representative images of the scratch wound assay of ECs treated with H-CM and P-CM (scale bar, 200 μm). e Quantitative analysis of the migration rates in d (n = 5). f Representative images of the tube formation assay in ECs treated with H-CM and P-CM (scale bar, 200 μm). g Quantitative analyses of the covered area, total branching points, total loops, and total tube length in f (n = 3). *P < 0.05, **P < 0.01 versus the control group; ^#P < 0.05, ^##P < 0.01 versus the H-CM group