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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Combination of indirect revascularization and endothelial progenitor cell transplantation improved cerebral perfusion and ameliorated tauopathy in a rat model of bilateral ICA ligation

Fig. 5

Effects of EMS and various treatments on cerebral microcirculation. A Regional blood flow and B partial pressure of brain tissue oxygen (PbtO2) of the control, BICAL, EMS and various treatment groups on the EMS (white bars) and non-EMS sides (gray bars) were measured simultaneously 3 weeks after BICAL. Comparison of the treatment efficacy between the EMS and non-EMS sides in each group was performed by the t-test. *p < 0.05. C On the EMS side, the reduction in regional blood flow induced by BICAL was rescued by EMS, EMS combined with SDF-1 or EPC treatment, but not by AMD3100 treatment. D EMS combined with EPC treatment significantly increased the BICAL-induced decrease in PbtO2. *p < 0.05, **p < 0.01, ***p < 0.001, n = 5–6

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Stem Cell Research & Therapy

ISSN: 1757-6512