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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia

Fig. 2

MIR155HG regulates MSCs through the NF-κB pathway. A Western blot analysis of P-ERK and ERK. B There was no significant difference in P-ERK/ERK expression between the two groups. C Western blot analysis of P-P65 and P65. D Phosphorylation level of p65 was significantly increased by MIR155HG overexpression (*p < 0.05). E Western blot analysis of P-mTOR and mTOR. F There was no significant difference in P-mTOR/mTOR expression between the two groups. G Western blot analysis of phosphorylation levels of P65 with or without NF-κB inhibitor BMS-345541. H Phosphorylation level of P65 was significantly decreased by sh-MIR155HG. BMS-345541 abolished the increased level of P-P65 caused by MIR155HG overexpression (*p < 0.05)

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