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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia

Fig. 5

The anti-apoptosis role of MIR155HG on MSCs under oxidative stress. A CCK-8 assay displayed that the IC50 value of H2O2 against MSCs was 226.5 μM. B, C Flow cytometry revealed that OE-MIR155HG reduced oxidative stress-induced apoptosis in MSCs. NF-κB inhibitor could counteract that protective effect of MIR155HG on MSCs (*p < 0.05). D, E ELISA assay showed that MIR155HG promoted the secretion level of HGF and VEGF in the supernatant of MSCs (*p < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512