Type of intervention | Details | Remarks |
---|---|---|
Pre-GDEPT | ||
Surgery | Prescapular mass removed | Patient presented to vet with incessant coughing. CT scan of the lungs revealed a 1.5Â cm diameter nodule present in the left caudal lobe of the lungs |
 | Route of administration | Dosage of MSC_CD::UPRT::GFP (Volume injected) | Oral 5-FC taken daily for 4 days (mg) | Patient weight (kg) | Quality of life observation |
---|---|---|---|---|---|
GDEPT treatment | |||||
GDEPT (Cycle 1) | Intravenous | 1.5 × 107 cells (7.5 mL)@Infused at 3 mL/hr | 500 | 3.75 | Patient experienced less coughing post-treatment |
Break in treatment due to COVID-19 lockdown | |||||
 GDEPT (Cycle 2) | Intravenous | 1.5 × 107 cells (7.5 mL) @Infused at 3 mL/hr | 500 | 3.65 | Patient responded well to treatment. No adverse reaction was observed |
 GDEPT (Cycle 3) | Intravenous | 1.5 × 107 cells (7.5 mL) @Infused at 3 mL/hr | 500 | 3.45 | Patient continues to respond well |
 GDEPT (Cycle 4) | Intravenous | 1.5 × 107 cells (7.5 mL) @Infused at 3 mL/hr | 500 | 3.70 | Less coughing observed |
 GDEPT (Cycle 5) | Intravenous | 1.5 × 107 cells (7.5 mL) @Infused at 3 mL/hr | 500 | 3.85 | Post-treatment CT scan revealed stable disease. Lung nodule did not grow in size |
Follow up actions | |||||
CT scan | Three month follow up | Disease continues to be stable. No progression of nodule size, nor extraordinary symptoms. Patient continues to experience good quality of life | |||
CT scan | One year follow up | Lung nodule of interest slightly increased in size. Incidental small nodule and lymph node enlargement was also reported. Suspected metastasis. All other symptoms remain unremarkable |