Fig. 1
From: The crosstalk between macrophages and bone marrow mesenchymal stem cells in bone healing
Source of MÏ•s in different tissues are different. a Resident MÏ•s are derived from yolk sac cells in embryonic stage. b Resident MÏ•s have the ability to differentiate themselves. c Resident MÏ•s existed in some special organs. d Bone tissues are able to produce large amount of monocytes. e Monocytes derived from bones migrate to blood vessels. f Monocytes have the ability to differentiate into hematopoietically derived MÏ•s and dendritic cells. g Hematopoietically derived MÏ•s and dendritic cells account for the majority of phagocytes in lots of organs in vivo