Fig. 2From: Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse modelA. Weight changes of mice fed regular chow or MCD during 6Ā weeks period. In each group, the number of mice was nā=ā6. **pā<ā0.01. B. Photographs of liver sizes of mice from different experimental groups (upper panel). The weights of each group of mice were recorded and counted (nā=ā6, below panel). **pā<ā0.01. ns: not significant. C. Plasma levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) of each mouse were recorded and counted (nā=ā6 in each group); *pā<ā0.05; D. Representative images of HE-stained liver sections of the indicated groups (microscope 40Ć). a mice with regular chow; b mice with MCD; c mice with MCD and intervention with control medium (CM) extract twice a week; d mice with MCD and intervention with hUC-MSC exosomes(Ex) twice a week. Scale barā=ā50Ā Ī¼m. E. Pathology scores for balloon-like degeneration, steatosis, and lobular inflammation of groups of liver sections (nā=ā6). *pā<ā0.05, **pā<ā0.01Back to article page