Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model

Fig. 2

A. Weight changes of mice fed regular chow or MCD during 6Ā weeks period. In each group, the number of mice was nā€‰=ā€‰6. **pā€‰<ā€‰0.01. B. Photographs of liver sizes of mice from different experimental groups (upper panel). The weights of each group of mice were recorded and counted (nā€‰=ā€‰6, below panel). **pā€‰<ā€‰0.01. ns: not significant. C. Plasma levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) of each mouse were recorded and counted (nā€‰=ā€‰6 in each group); *pā€‰<ā€‰0.05; D. Representative images of HE-stained liver sections of the indicated groups (microscope 40Ɨ). a mice with regular chow; b mice with MCD; c mice with MCD and intervention with control medium (CM) extract twice a week; d mice with MCD and intervention with hUC-MSC exosomes(Ex) twice a week. Scale barā€‰=ā€‰50Ā Ī¼m. E. Pathology scores for balloon-like degeneration, steatosis, and lobular inflammation of groups of liver sections (nā€‰=ā€‰6). *pā€‰<ā€‰0.05, **pā€‰<ā€‰0.01

Back to article page