Fig. 3

In vitro analysis of islet survival and function following exposure to pro-inflammatory cytokines: a representative confocal images and results of b live/dead, c MTT, and d high-glucose-stimulated insulin secretion assays of tested groups (i.e., Islets, e-Islets, m-Islets, em-Islets, and emf-Islets). Blue: live cells stained with Hoechst. Red: dead cells stained with PI. Green: AD-MSCs stained with FDA. Scale bar = 50 μm. Significant differences: b–d ^aP < 0.05: Islets vs. m-Islets or em-Islets or emf-Islets; ^bP < 0.05: m-Islets vs. em-Islets or emf-Islets; ^dP < 0.05: em-Islets vs. emf-Islets (one-way ANOVA post hoc Tukey test)