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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Tumor stemness score to estimate epithelial-to-mesenchymal transition (EMT) and cancer stem cells (CSCs) characterization and to predict the prognosis and immunotherapy response in bladder urothelial carcinoma

Fig. 3

Transcriptomic and metabolic characteristics of the TS-related gene clusters. A Unsupervised clustering of 61 TS-related genes in the TCGA BLCA cohort. Red represents high expression, and blue represents low expression. B Kaplan–Meier curves for the two TS-related gene clusters of patients. The log-rank test showed an overall p < 0.001. C Boxplot of 13 EMT biomarkers for two TS-related gene clusters in the TCGA BLCA cohort. D Boxplot of ssGSEA scores of stem cell gene set for two TS-related gene clusters in the TCGA BLCA cohort. E Boxplot of stromal score, immune score, and ESTIMATE score for two TS-related gene clusters in the TCGA BLCA cohort. F Boxplot of 22 immune cell content for two TS-related gene clusters in the TCGA BLCA cohort. Wilcox test, *p < 0.05, **p < 0.01, ***p < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512