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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Tumor stemness score to estimate epithelial-to-mesenchymal transition (EMT) and cancer stem cells (CSCs) characterization and to predict the prognosis and immunotherapy response in bladder urothelial carcinoma

Fig. 4

The relationship between TS characteristics and TS score in BLCA. A Principal component analysis (PCA) based on 61 TS-related genes expression. B Alluvial diagram of TS clusters and TS-related gene distribution in groups with different TS scores. C GSEA analysis of high/low TS score group in TCGA BLCA cohort. D The correlation network between EMT biomarkers and TS score in TCGA BLCA cohort. Spearman, Cor > 0.3 and p < 0.001. E The correlation between TS score and ssGSEA score of stem cell gene set in TCGA BLCA cohort. Spearman, Cor = 0.65 and p < 0.001. F The correlation between TS score and stromal score in TCGA BLCA cohort. Spearman, Cor = 0.75 and p < 0.001. G The correlation between TS score and immune score in TCGA BLCA cohort. Spearman, Cor = 0.51 and p < 0.001. The oncoPrint was constructed using high TS score group (H) and low TS score group (I). Individual patients are represented in each column in TCGA BLCA cohort

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Stem Cell Research & Therapy

ISSN: 1757-6512