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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Endothelial colony forming cell administration promotes neurovascular unit development in growth restricted and appropriately grown fetal lambs

Fig. 6

A–D Representative photomicrographs of MMP-9 immunohistochemical staining in the sCWM. E Data are mean ± SEM for % of identified blood vessels staining positively for MMP-9 expression as calculated in the Cx, PVWM, sCWM, and SVZ from AGA (Black; n = 7), FGR (Grey; n = 5), AGA + ECFC (Black patterned; n = 6), and FGR + ECFC (Grey patterned; n = 6). Data were examined using a two-step analysis, with AGA and FGR compared first via unpaired t test, then all groups compared using two-way ANOVA with FGR and ECFC treatment as variables. *P ≤ 0.05 using unpaired t test for AGA versus FGR. Two-way ANOVA results for main effects (PECFC, PFGR) and interaction (PINT) for each brain region are presented below the relevant graph (NS = P > 0.05)

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