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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Long non-coding RNA H19 regulates matrisome signature and impacts cell behavior on MSC-engineered extracellular matrices

Fig. 5

miR-29c-3p expression in bone samples and the impact of miR-29c-3p in H19 levels. a Box and whiskers plots show miRNA expression levels (2−ΔCq) in bone samples from patients with fragility fractures (FF) or osteoarthritis (OA). b Adjusted p-values for miRNA expression considering age. c Expression levels of H19 and miR-29c-3p on MSC from healthy and FF patients (N = 3). d Effect of the modulation of the levels of miR-29c-3p on the lncRNA H19 expression, 3 days post-transfection in osteogenic-inducing conditions (N = 6). (Mimics-NC: MSC transfected with scrambled miRNA mimics negative control; Mimics: miR-29c-3p transfected MSC; Inhibitor-NC: MSC transfected with scrambled miRNA inhibitor negative control; Inhibitor: miR-29c-3p-inhibitor transfected MSC)

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