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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats

Fig. 2

HFSCs and HFSCs/HGF ameliorated neuron apoptosis. A–E Representative photographs of TUNEL-positive cells in all groups. Normal nucleus was stained blue and TUNEL-positive cells green (arrows). Tissue samples were collected from the penumbra of ischemic cerebral hemispheres. Scale bar = 100 µm. F The quantitative analysis of TUNEL-positive cells in different groups. G Representative western blot bands of apoptosis-related proteins in different groups. H–K Quantification of Bax, Bcl-2, Bcl-2/Bax and cleaved Caspase-3 expression. All the quantifications were undertaken based on the data of 6 independent experiments and normalized to β-actin. Values are the mean ± SD. *P < 0.05 Saline group vs. Control group, #P < 0.05 HFSCs group vs. Saline group, ∆P < 0.05 HFSCs/HGF group vs. HFSCs/Vehicle group, n = 6

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