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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: A novel chondrocyte sheet fabrication using human-induced pluripotent stem cell-derived expandable limb-bud mesenchymal cells

Fig. 3

Engraftment of ExpLBM-derived chondrocyte sheets in X-SCID rats. A A diagram of ExpLBM-derived chondrocyte sheet transplantation procedures. B The knee joints four weeks after transplantation. C Histological examination of osteochondral defects that have been engrafted with ExpLBM-derived chondrocyte sheets. Four weeks after transplantation, the knee joints were fixed, and tissue sections were stained with H&E, Safranin O, or toluidine blue, or antibodies against human VIMENTIN, COL2, ACAN, or COL1. Representative images are displayed (scale bars: 200 µm)

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