Fig. 6

PGE2-MSCs regulate macrophage polarization and cytokine production. A Representative immunofluorescence images of F4/80 expression (red) in LPS-induced ALI mice. Scale bar, 200 µm. B Quantification of F4/80 + cells in each group. C Immunofluorescence images of CD206 expression (green) in LPS-induced ALI mice. Scale bar, 100 µm. D Quantification of CD206 + cells in each group. E–G qRT‒PCR analysis of macrophage-related gene expression (Arg1, CD206, IL-6 and iNOS). Data are represented as the mean ± SEM. *P < 0.05 vs ALI;^#P < 0.05 vs PBS; ^&P < 0.05 vs MSC