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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Single-stage transplantation combined with epidermal stem cells promotes the survival of tissue-engineered skin by inducing early angiogenesis

Fig. 3

Proangiogenic effects and RNA-seq of KEGG pathways enriched in RVECs exposed to the supernatant of EpSCs. A Patterns of EpSCs under different culture conditions. The ADM + EpSCs group represents the EpSCs cultured in the ADM sheets, and the EpSCs group represents the EpSCs cultured on the dish. KFSM and ADM were used as the control groups. B Representative images of the tube formation ability of rat VECs stimulated with the supernatant under different conditions. Scale bar: 100 μm. C Quantification of tubule formation results. D Volcano plot of EpSCs vs. the control group. E Volcano plot of the EpSC + ADM group vs. the control group. F Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of EpSCs vs. the control group. G Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of the EpSC + ADM group vs. the control group

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