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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Inflammatory stimulation of astrocytes affects the expression of miRNA-22-3p within NSCs-EVs regulating remyelination by targeting KDM3A

Fig. 4

EVs derived from LPS-As-stimulated NSCs promoted the differentiation of NSCs into oligodendrocytes. A, B The immunofluorescence staining data showed that after coculturing with NSCs-EVs, As-NSCs-EVs or LPS-As-NSCs-EVs cocultured for 7 days, the NSCs treated with LPS-As-NSCs-EVs had the highest percentage of Cnpase-positive or MBP-positive oligodendrocytes and the lowest percentage of GFAP-positive astrocytes (n = 5; data are the mean ± S.D; *p < 0.05, ns p > 0.05; scale bars, 100 μm)

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