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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model

Fig. 3

Increase in pain in rats with mild OA is induced by MSCs but not MSC-EVs. A Rear left/rear right (RL/RR) ratio measured on dynamic weight bearing (DWB) and B 50% paw withdrawal threshold measured on von Frey. No animals or data points were excluded from these analyses, n = 12 per group. Graphs represent mean ± 95% confidence interval, p values in graphs are reported with asterisks where p ≤ 0.05 is *, p ≤ 0.01 is **, p ≤ 0.001 is *** and p > 0.05 is not significant

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Stem Cell Research & Therapy

ISSN: 1757-6512