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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway

Fig. 6

MSCs and IronQ combined treatment regulated the Mincle/syk signaling pathway to improve ICH outcomes. A The results of double immunofluorescence displayed co-expression of F4/80 with Mincle in the ipsilateral striatum of mice brain tissue in each group (n = 5 for each group). Respective change in color showing co-localized signals in merged figures corresponds to Red + Green = Yellow; Red + Blue = Magenta. Scare bar = 100 μm (top panel). The white box areas are shown at higher magnification in the bottom panel. B-E The results and analyses of western blot of Mincle, p-syk, and p-NFκB-p65 protein expression in mice with ICH in each group (n = 5 for each group; *P < 0.05, and ****P < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512