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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Cell therapy in end-stage liver disease: replace and remodel

Fig. 1

Cell sources and entry routes for cell therapy. Replacement and remodelling are the two primary purposes of cells deployed in cell therapy. Before cell transplantation, bile duct epithelial cells, pluripotent stem cells, and foetal liver progenitor cells must be differentiated into hepatocytes in vitro. Following transplantation, these cells proliferate within the liver and replace the host hepatocytes. Additionally, mesenchymal stem cells, macrophages, and hematopoietic progenitor cells can remodel the hepatic microenvironment. The liver, spleen, and peritoneum are all potential sites for cell transplantation

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