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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis- and senescence-related genes in swine adipose-derived mesenchymal stem/stromal cells

Fig. 8

Obesity/dyslipidemia-driven dysregulation of 5hmC epigenetic marks on apoptosis- and senescence-related genes in human adipose-derived MSCs. A Heat maps showing high (left; n = 16) and low (right; n = 52) 5hmC levels in genes filtered by apoptotic process (GO:0006915) in human Obese- versus Lean-MSCs. B Heat map showing high (AAAS, n = 1) and low (n = 15) 5hmC levels in genes filtered by the Cellular Senescence REACTOME Superpath or the GO term for Cellular Senescence (GO:0090398) in human Obese- versus Lean-MSCs. n = 5 per group

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Stem Cell Research & Therapy

ISSN: 1757-6512